Endometriosis Under Control: How to Increase Your Chances of Getting Pregnant Successfully 

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27.03.2026

Pacientka v gynekologicke ordinaci Prague Fertility Centre

Endometriosis is a chronic condition with a wide range of symptoms that can significantly affect a woman’s everyday life — from painful periods to long-term fatigue or recurring pelvic pain. Modern medicine offers proven ways to effectively manage these symptoms and reduce the long-term impact of the disease. March, as Endometriosis Awareness Month, is therefore an ideal opportunity to highlight that professional help is available — and that solutions may be closer than they seem.

What is endometriosis and where does it occur?

Endometriosis is a chronic condition in which tissue similar to the lining of the uterus is found outside the uterine cavity — most commonly on the ovaries, fallopian tubes, or peritoneum. These lesions respond to hormonal changes during the menstrual cycle, which can lead to inflammation, adhesions, and pain. According to the World Health Organization, it affects approximately 10% of women of reproductive age. Typical symptoms include heavy and painful periods, chronic pelvic pain, or pain during intercourse — symptoms that should never be considered normal.”

How does endometriosis affect fertility?

From a fertility perspective, endometriosis is one of the significant factors that can make natural conception more difficult. According to the European Society of Human Reproduction and Embryology, it occurs in up to 30 – 50% of women dealing with infertility. The condition may affect egg quality, impair the patency of the fallopian tubes, or alter the uterine environment, making embryo implantation more difficult. It is important to emphasize, however, that a diagnosis of endometriosis does not mean pregnancy is impossible — it often simply requires a targeted and professionally guided approach.

The most common effects of endometriosis on fertility

  • reduced egg quality due to an inflammatory environment
  • impaired fallopian tube patency
  • less favorable conditions for embryo implantation
  • hormonal imbalance affecting ovulation
  • adhesions in the pelvic area

What treatment options are available?

Treatment options always depend on the individual situation of the patient—her age, the extent of the disease, and her reproductive plans. They may include hormonal therapy, surgical intervention, or assisted reproduction methods. Modern reproductive medicine emphasizes a personalized approach and the combination of treatments to ensure maximum effectiveness while remaining as gentle as possible. The goal is not only to alleviate symptoms but, above all, to support the chances of successful conception.


From the perspective of current medicine, a key factor in endometriosis is also endometrial receptivity — the ability of the uterine lining to accept an embryo at the right moment. In some patients, this process may be disrupted due to altered cellular signaling and hormonal response of the endometrium. In practice, this means that even a high-quality embryo may not have optimal conditions for implantation if the timing of transfer is not ideal. For this reason, advanced diagnostic methods are used in indicated cases, such as the Endometrial Receptivity Test, which we offer at our clinic. The results can help determine the so-called implantation window and better time the embryo transfer.


👉 If you want to prepare your body properly for IVF, read also: What does our doctor recommend?

There is hope: The path to a baby may not be far away

The good news is that despite a diagnosis of endometriosis, there are now effective ways to significantly increase the chances of getting pregnant. When women place themselves in the hands of experienced specialists who can properly set up both diagnostics and treatment, the journey to a desired baby may not be as distant as it first seems. Modern reproductive medicine offers tailored solutions for each patient, and in many cases IVF specialists can significantly improve the chances of a successful pregnancy.

Expert care at Prague Fertility Centre

At Prague Fertility Centre, we have long focused on endometriosis and understand how crucial timely and accurate diagnosis, as well as subsequent treatment, are. Our team includes, for example, endometriosis specialist Dr. Lea Libičová, who specializes in comprehensive care for patients with this condition. Our other IVF specialists are equally prepared to support women affected by endometriosis — they provide expert guidance, a personalized and empathetic approach, and stand by their patients throughout their journey to parenthood.

If this topic is relevant to you and you would like to learn more, we will be happy to discuss everything with you during a no-obligation consultation.

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