Preimplantation genetic testing of monogenic diseases

Preimplantation genetic testing of monogenic diseases is a procedure that detects the presence of a genetic defect or abnormality of the embryos before they get transferred into the mother’s womb. This examination is recommended for patients who are carriers of certain genetic diseases or chromosomal translocations. It ensures that faulty embryos will not be transferred.


Preimplantation genetic testing of aneuploidies and structural chromosomal defects

Preimplantation genetic screening is designed to test for a variety of genetic diseases. In fact, that is the only difference from PGT-M, which detects particular diseases. It helps reveal the possible genetic diseases of an embryo in cases when parents do not have a history of a genetic disease in their lineage.

Reliability of traditional PGS method

It is important to point out that the ordinary PGT-M/PGT-A tests are not completely reliable. That is why, at Prague Fertility Centre, we have developed an enhancement of the reliability of genetic testing by implementing new revolutionary methods.

The methods we combine with PGT-M/PGT-A testing in our clinic offer significant benefits to our patients:

  • They increase the chance of conception
  • They reduce the chance of miscarriage
  • They reduce the risk of having an unhealthy baby

Innovative PGT-M/PGT-A methods only at Prague Fertility Centre


All embryos meant for PGT-A/PGT-SR/PGT-M tests are continuously monitored by time-lapse technology.

The monitoring is not invasive, meaning that it does not affect the environment of the embryo at all. Time-lapse technology can detect a faulty embryo at the right time before its selection for further PGT-M/PGT-A testing, which is done only with embryos that have undergone correct development. This process ensures that only the highest-quality embryos will be selected for genetic testing and get to the transfer.

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