A gentle procedure that reduces handling time in the selection of best-quality sperm.
MICHSS simulates the journey of sperm through the fallopian tubes to the uterus. Conventional methods of sperm selection typically use centrifugation and subsequent tracking of sperm motility. MICHSS, in contrast, reduces sample handling time from approximately 2 hours to just 30 minutes. Sperm are therefore exposed to the external environment for a much shorter time and the risk of DNA fragmentation and mechanical damage is substantially reduced.
The entire process involves only one step, during which sperm are monitored for their ability to travel through the chip mechanism into the central stream of the device. MICHSS is essentially a more modern and efficient variant of the previously widespread magnetically activated selection procedure magnetic activated cell sorting — MACS.
MICHSS — sperm selection using microfluidic chip I PFC
Sperm selection using MICHSS microfluidic chip technology maximises the efficiency of daily laboratory work during sample analysis. It is our first choice for men with sperm in the ejaculate. In PFC laboratories, we use the most modern separation microfluidic chip-based device ZyMot. In cases of azoospermia, or is the complete absence of sperm in the ejaculate, we then explore specialised methods of surgical sperm retrieval through MESA/TESE (microsurgical sperm retrieval) and possibly selection by LAISS (laser assisted selection of non-motile sperm).
Our andrology specialists can explain how we proceed with the examination and treatment of male factor infertility to find the best method for each individual.
You can learn more about our comprehensive approach to fertility treatment on both the male and female side directly from your IVF coordinator.
Preimplantation genetic screening and diagnosis — prevention of nesting failure and transmission of genetic defects.
Modern microsurgical sperm collection methods from the testicles and epididymis in the case of low / zero sperm concentration.
Intracytoplasmic injection of sperm directly into the egg in order to overcome barriers and increase chances of fertilisation.
An innovative polarising microscopy method for monitoring egg maturity to determine the correct timing for fertilisation.
Monitored embryo development over 48 hours to select the embryo with the highest potential for implantation.
A real-time embryo development tracking system to select the embryos with the highest potential for nesting.
A special solution for protecting the embryo and facilitating its connection with the uterine lining.
Laser-assisted hatching is a non-invasive method for facilitating an embryo to leave the protective shell and promote nesting.
Asynchronous embryo transfer is a method in which we transfer 2 embryos of different ages to increase chances of succesful implantation.
ERA test, beReady — advanced analytical methods of the genetic profile of the uterine lining to determine the timing of implantation.
Preservation of eggs and embryos for potential future use by fast, gentle and efficient freezing.